The Mojo Shot™ Specialist

DuPont Institute

Mary C. DuPont, MD, FPMRS, FACS

Aesthetic Specialist & Surgeon located in Chevy Chase, MD

Sexuality is a complex process that is influenced by psychological as well as physiological factors. Sexual dysfunction can be used to describe problems with desire, arousal, orgasm, or pain with sex. It can be influenced by aging, health status, socio-economic status, societal and religious beliefs, and personal experience.

The Mojo Shot™️

  • Up to 10% of women never achieve an orgasm (primary anorgasmia) and
  • Only ~20-25% of women are always able to achieve orgasm during intercourse.
  •  Approximately one third of women report orgasmic difficulties and intimacy problems affect 50%.


Not surprisingly, couples who were happiest in their relationships reported

the fewest sexual dysfunction problems. Studies evaluating sexual

satisfaction among lesbian, bisexual, and heterosexual found no significant

differences in the number of orgasms experienced.



For the majority of women, orgasms are reached more easily during

masturbation than during intercourse as deep penile thrusting and the male

superior position is not ideal in providing clitoral stimulation. The

distal one third of the vagina is the most sensitive as it is rich in nerve

endings. The upper two thirds of the vagina is not as sensitive so deep

penile thrusting is less apt to trigger an orgasm.


In 2004, an interesting MRI study appeared in the Journal of Sexual Medicine

that correlated the size and location of the clitoris to sexual health.

Small clitoral size and location further from the vaginal opening was

linked to a greater incidence of anorgasmia. The Mojo Shot™️is aimed to enhance clitoral sensitivity.



The in-office The Mojo Shot™️ treatment involves an innovative regenerative

medicine approach that not only offers sexual enhancement of orgasms, it

rejuvenates the vaginal tissue to help you feel firmer, healthier, and

perform better sexually. The Mojo Shot™️ is not a medication, but instead

is a form of advanced stem cell therapy. Stem cells have the wonderful

capacity to develop into specialized cell types, from muscle cells to brain

cells. By using your undifferentiated stem cells to stimulate your body’s

natural production process, new cells in and around the injection sites are

produced. This platelet matrix contains numerous growth factors that

result in cell division, collagen production, new blood flow, and cell



Dr. DuPont will take a sample of your blood and will remove the platelet-rich

fibrin (PRF) after a centrifuge process. The concentrated platelets and

growth factors will then be injected back into your upper vaginal wall and

clitoris. Topical anesthetic is used for the quick procedure to make it



The Mojo Shot™️ differs from the O-shot® in that platelet rich fibrin

(PRF) is used and not platelet rich plasma (PRP). This fibrin matrix

results in PRF growth factors being released more gradually, being

expressed more strongly, and having a more durable effect on cell growth

and differentiation. The analogy that we like to use is that you can build

a stronger and more durable structure if you have a sound foundation upon

which to build. PRF is also 100% natural as it avoids the use of

additives. PRF is also preferred as it contains stem cells and PRP does

not contain stem cells.




What Conditions Are Suitable for The Mojo Shot™️treatment?

  • Pain with intercourse
  • Problems with achieving orgasm
  • Dermatologic conditions such as lichen sclerosus, episiotomy or vaginal
  • scars
  • Mild laxity of the vagina
  • Mild stress urinary incontinence
  • Diminished vaginal lubrication
  • Vulvodynia







Dr. DuPont recommends a schedule of up to 3 injections over 5 months for

maximal results and then annual maintenance injections. Over 85% of women

have reported a long lasting improvement in the following after injection:

  • Greater intensity of clitoral stimulation (may secondarily enhance sex drive)
  • Improved vaginal lubrication
  • Improvement in urinary incontinence
  • Improved vaginal/vulva tissue health
  • Improvement in achieving orgasms


Dr. DuPont may recommend a booster MonaLisa Touch™️ laser treatment

(vaginal CO2 laser) in addition to The Mojo Shot™️in order to counter

symptoms after childbirth or menopause such as vaginal dryness, painful

intercourse and urinary incontinence. MonaLisa Touch™️ and The Mojo Shot™️

work synergistically to improve tissue health, vaginal tone, and heighten

clitoral sensitization.


Approximately 85% of women experience a benefit in vaginal health and

orgasms as a result of regenerative medicine. There are numerous options

for female orgasmic problems to include medical and sex therapy.


If you are interested in enhancing your sex life, contact Dr. DuPont at

DuPont Aesthetics to schedule your consultation.